Tumor miofibroblástico inflamatorio de colon

Paciente de 4 años con tumor en colon transverso, el diagnóstico (por histología e inmunohistoquímica) fue tumor miofibroblástico inflamatorio

ALK-1 Inmunohistochemistry

 An inflammatory myofibroblastic tumor (IMT) was first described in 1937¹ as a primary lung tumor. The tumor consists of the proliferation of fibroblastic-myofibroblastic cells admixed with inflammatory infiltrate.

Independent of the location, IMTs are more common in children and young adults, but patients of any age and sex can be affected.¹ Besides the lung, IMTs can also occur in the retroperitoneum, mediastinum, spleen, brain, pancreas, liver, or GI tract as single or multiple tumors.^2,3,4,5,6,7 Although most authors admit that an ITM is a benign tumor, the recurrences and metastases presented in some of the reported cases^1,6 may lead to a reclassification of this tumor as having uncertain malignant potential.

In the colorectal segment, the first case of IMT was described in the rectum by Coffin et al³ in 1995. Between 1995 and 2012, according to our knowledge, the number of reported cases rose to 24,^1–17

(Simona Gurzu, 

Tivadar Bara, 

and Ioan Jung. Inflammatory Myofibroblastic Tumor of the Colon. 

JCO Apr 1, 2013:e155-e158; published online on January 28, 2013)